The Anti-Oxidant Effects of Vitamins on Lead-Induced Reproductive Toxicity in Male Wistar Rats

Aim: The current study investigated the anti-oxidant effects of vitamins on lead-induced reproductive toxicity in male wistar rats.
 Study Design: A total 48 Wistar rats divided into 6 groups 8 per group were used this study. Group 1 served as positive control and was given normal animal feed water ad libitum. 2 negative administered 10mg/kg body weight lead acetate (Pb) only, 3 with 200mg/kg vitamin C 4 1000IU/kg E 5 while E. administration test substances lasted for weeks after which animals sacrificed. Blood samples collected assayed hormones. Semen also extracted from testis assay sperm parameters epididymis harvested histological analyses.
 Place Duration Study: carried out Department Human Physiology University Port Harcourt it a period months.
 Results: results showed that significantly decreases concentration hormones, destroys architecture epididymis. antioxidants found to ameliorate damages done by reproduction histology epididymis.
 Conclusion: It therefore concluded anti-oxidants may be suitable substitutes chelating agents ameliorating function rats.